OligoLocator Crack With License Key Free







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Version 1.1 provides a variety of small fixes.
1. You can now select the selection template of oligonucleotides based on their aligning nucleotides.
2. Various other small bug fixes.
In the next version, I will provide an option to remove the color highlighting of the matching oligonucleotides.
As usual, you can download the new version at the OligoLocator For Windows 10 Crack webpage:

If you have any questions, ideas or comments, please let me know.
Laszlo Szepedŭsz
oligoLocator 1.1
Have you ever used the software to align DNA oligonucleotides? Then you can try OligoLocator.
What is OligoLocator?
OligoLocator is a simple, Java based application designed to identify the position of oligonucleotides within nucleic acid sequences with varying degrees of mismatch between the two.
What’s New in OligoLocator:
Version 1.0 provides an initial release.
In the next version, I will add features like an option to remove the color highlighting of the matching oligonucleotides.
As usual, you can download the new version at the OligoLocator webpage:

If you have any questions, ideas or comments, please let me know.
Laszlo Szepedŭsz
oligoLocator 1.0

OligoLocator Crack + Free For Windows

OligoLocator finds the position of oligonucleotides in sequence, within a multiple sequence alignment (MSA) of protein sequences. The MSA should be in fasta format. Note that you should first convert the sequences in the MSA into fasta format by using the “fasta2fasta” tool from the “seqret” suite.
OligoLocator uses the free oligonucleotide database (FOND) \cite{FOND1} \cite{FOND2} as a reference. The database contains all known oligonucleotide sequences available from the literature and are well annotated.
The program looks for oligonucleotides (sequence length ≥ 3 nt), that have a position of +1 to -1 nt from the translated start or stop codon of the gene in question.
The program also allows for a mismatch (±2 nt) to be considered. For example, when looking for oligonucleotides within coding regions (e.g. MSA aa) the program considers the base at the 5′ end (A, C, T or G). When looking for oligonucleotides in intronic regions, the program considers the base at the 3′ end (A, C, T or G). The program also allows a mismatch to be considered. For example, when searching for oligonucleotides in coding regions (e.g. MSA aa) the program considers the base at the 3′ end (A, C, T or G).
The program also allows for negative selection, where all base at the 5′ end (A, C, T or G) are considered, and the base at the 3′ end (A, C, T or G) is ignored. This allows for negative selection to be considered in intronic regions.
Several oligonucleotide parameters are used, and are automatically calculated as part of the program:
– Oligonucleotide length
– Gap location (minimum of 3 nt)
– Minimum overlap (base + gap)
– Number of possible mismatches per oligonucleotide
– Number of mismatches allowed (excluding that one between the 3′ and 5′ bases)

PDB Location:
[Email protected] | [Kiefer lab](
[Kiefer lab](

OligoLocator Crack + [April-2022]

OligoLocator has been developed to assist in the design of DNA probes with the expectation of finding such DNA binding sites within an unknown sequence. The expected mismatch between probe and target is a very important factor in selecting suitable probe sequence for the study of a particular gene or genomic segment.

OligoLocator successfully identifies the exact position of the mismatched oligonucleotide within a DNA sequence. The application is able to identify the specific mismatch within the oligonucleotide. This allows the DNA probe designer to choose suitable oligonucleotides for a particular target sequence.

If no position of mismatches are present within the sequence, then the total number of mismatches for the oligonucleotide chosen for the specific application will be shown. OligoLocator will also show the number of matched and unmatched bases and the sequence of bases located at the mismatched position.

For any given mismatch, the application will indicate the position of the mismatch within the sequence, its frequency (number of matching and unmatched bases), as well as the number of mismatches per base along with the complementary strand. The application will also indicate the number of bases that are complementary and unmatched to the oligonucleotide chosen.

The software performs an optimal alignment of the probe against the target. The application will display the exact position of the oligonucleotide within the sequence, the number of mismatches, the expected frequency of mismatches, the sequence of mismatches, the mismatched base, the number of matched and unmatched bases and the number of complementary and unmatched bases. The software will also show the expected frequency of mismatches per base along with the complementary strand and the nucleotide composition.

Probe Design

As described above, OligoLocator uses the same base calling algorithms described in the literature. The application can design single-stranded or double-stranded DNA probes that will hybridize to any region within a DNA sequence. The application allows the user to specify the nucleotide composition, the length of the oligonucleotides and the GC content for the DNA probe. The user can specify the oligonucleotide mismatch frequency between the probe and the DNA sequence, and can choose whether to use double stranded or single stranded oligonucleotides.

OligoLocator: Database Features

Database: OligoLocator uses the database described by Hwang & Nelson, 2000, which is available at

What’s New in the?

The software performs a sliding window of a specified size through the source sequence and compares the current sequence to the reference sequence to determine the position of the start of each oligonucleotide.

In most cases you will be able to point the mouse at the icon on the GUI for the application and click to find each match. You may also right click the icon and select the “Find In Sequence” from the context menu. This will show you the position of the oligonucleotide within the sequence, the matching nucleotide sequence and the match quality.

Copyright 2001 Anders Knudsen
License: GNU GPL

The purpose of this application is to request funds to purchase a Zeiss LSM 510 META Confocal Microscope, and associated accessories, for use by a group of NIH-funded investigators who work at The University of Michigan and in collaboration with The University of Michigan and The University of Alabama-Birmingham. The microscope will be housed in a shared biomedical research core facility, which currently includes 2 existing confocal microscopes. The Zeiss LSM 510 META is the most recent addition to the confocal microscope line. The requested instrument will replace a 10 year old BioRad Radiance confocal and it will serve the needs of a group of 19 NIH-funded investigators who have peer-reviewed funding from the National Institute of Health totaling $3.4 million in direct costs. The requested instrument will provide approximately 35 percent cost savings when compared to currently available instrumentation at other institutions in the area. The requested equipment will be used to visualize subcellular protein expression in cultured cells, secretory cells, and whole mount tissues, as well as to image intracellular calcium signals. The requested equipment will also be used to study protein expression in living zebrafish embryos.The present invention relates to a method and an apparatus for winding a strand of yarn on a take-up core in a device for processing textile yarns.
In the following description, the term “yarn” is used generically to refer to a plurality of strands of yarn or other strands, filaments, fibers, threads, etc. which are twisted together to form yarns.
In many known textile processing machines, a take-up device is provided with a spindle which is driven in rotation and a take-up core which is rotated at a speed slightly lower than the spindle so as to draw the yarn out of the spindle, and to wind it onto the take-up core.
The yarn is drawn out of the spindle by being sucked into the spindle.
Known methods of doing this are of the kind described, for example, in Italian Patent Application No. MI99A000378 and U.S. Pat. No. 4,685,239. In particular, these two patent applications disclose a method of drawing out yarn from a spinning tube in which the drawing is done by means of the suction

System Requirements For OligoLocator:

Windows 7, Vista, XP.
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